Main artery WSJ Crossword Clue

By Narcissa Kh /

Crossword Answer

1 ? A
2 ? O
3 ? R
4 ? T
5 ? A
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      Hint 1

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      Think of the grand highway that carries life's essential flow from the heart.

      Hint 2

      meaning
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      ????? is the main artery that carries blood from the heart to the rest of the body.

      Hint 3

      explanation
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      The clue 'Main artery' refers to the largest and most significant artery in the human body, which is the ?????. In anatomical terms, the ????? is the principal artery that carries blood from the heart to the rest of the body.

      Hint 4

      another clue
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      major vessel, Significant blood line, Artery from the heart, Conduit from a ventricle, Major artery

      Clue Analysis

      The clue “Main artery” is a classic crossword staple, frequently appearing in puzzles like the WSJ crossword. For the puzzle dated April 7 2026, the definitive 5-letter answer is: AORTA.

      Expert Tip: When you’re stuck, try to analyze the structure of the clue itself. Is it a direct definition, a pun, a fill-in-the-blank, or a pop culture reference? Identifying the type of clue you’re dealing with is a key skill for improving your solving speed.

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      Main artery Crossword Clue