Main artery WSJ Crossword Clue

By Last Update: APR 7, 2026 Follow on Google

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Frequently Asked Questions About This Clue

The most common and recent 5-letter answer for "Main artery" is AORTA.

The clue 'Main artery' refers to the largest and most significant artery in the human body, which is the aorta. In anatomical terms, the aorta is the principal artery that carries blood from the heart to the rest of the body.

Aorta is the main artery that carries blood from the heart to the rest of the body.

Important blood line, major vessel, Significant blood line, Artery from the heart, Conduit from a ventricle

WSJ Crossword - July 28, 2025 - WSJ Crossword - April 07, 2026

The clue “Main artery” is a classic crossword staple, frequently appearing in puzzles like the WSJ crossword. For the puzzle dated April 7 2026, the definitive 5-letter answer is: AORTA.

Expert Tip: When you’re stuck, try to analyze the structure of the clue itself. Is it a direct definition, a pun, a fill-in-the-blank, or a pop culture reference? Identifying the type of clue you’re dealing with is a key skill for improving your solving speed.

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