Immune system agent WSJ Crossword Clue

By Narcissa Kh /

Crossword Answer

1 ? T
2 ? C
3 ? E
4 ? L
5 ? L
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      Hint 1

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      Think of the body's microscopic warriors that identify and attack invaders.

      Hint 2

      meaning
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      A ????? is a type of white blood cell that is essential for the immune response.

      Hint 3

      explanation
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      The clue refers to a component of the immune system. '?????' is a type of lymphocyte that plays a central role in cell-mediated immunity, making it a key 'agent' of the immune system.

      Hint 4

      another clue
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      Small component of an immune response

      Clue Analysis

      The clue “Immune system agent” is a classic crossword staple, frequently appearing in puzzles like the WSJ crossword. For the puzzle dated March 21 2026, the definitive 5-letter answer is: TCELL.

      Expert Tip: When you’re stuck, try to analyze the structure of the clue itself. Is it a direct definition, a pun, a fill-in-the-blank, or a pop culture reference? Identifying the type of clue you’re dealing with is a key skill for improving your solving speed.

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      Immune system agent Crossword Clue