Number discovered in the 1500s NYT Crossword Clue

By Date: OCT 24, 2025 Follow on Google

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The most common and recent 5-letter answer for "Number discovered in the 1500s" is ETHER.

The clue uses 'number' in the sense of something that numbs, rather than a numerical value. Ether is a chemical compound known for its anesthetic properties, which can numb pain. It was discovered in the 1500s and later used as an anesthetic in surgeries.

This clue was last seen in the NYT Crossword on October 24, 2025.

Ether is a volatile, highly flammable liquid used as an anesthetic and solvent.

Anesthetic of the past, Substance used like chloroform, Thin air, so to speak, Old-timey dental anesthetic, Early anesthetic

The answer to “Number discovered in the 1500s” in the New York Times puzzle October 24 2025 is ETHER. Quite straight and simple! Complete your daily NYT Mini challenge with this solution.

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