Significant blood line WSJ Crossword Clue

By Narcissa Kh / May 8, 2026

Crossword Answer

1 ? A

2 ? O

3 ? R

4 ? T

5 ? A

Hint

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Your Answer 5 Letter

Current guess: —

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Hint 1

hint

Reveal Hint

Think of the grand highway that all the red rivers flow from.

Hint 2

meaning

Reveal Hint

The ????? is the main artery in the human body, supplying oxygenated blood to the circulatory system.

Hint 3

explanation

Reveal Hint

The clue uses the word 'significant' to indicate something important or crucial, and 'blood line' cleverly refers to a major blood vessel. The ????? is the main artery that carries blood away from the heart to the rest of the body, making it a 'significant blood line.'

Hint 4

another clue

Reveal Hint

major vessel, Artery from the heart, Conduit from a ventricle, Major artery, Iliac artery feeder

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Clue Analysis

The clue “Significant blood line” is a classic crossword staple, frequently appearing in puzzles like the WSJ crossword. For the puzzle dated May 8 2026, the definitive 5-letter answer is: AORTA.

Expert Tip: When you’re stuck, try to analyze the structure of the clue itself. Is it a direct definition, a pun, a fill-in-the-blank, or a pop culture reference? Identifying the type of clue you’re dealing with is a key skill for improving your solving speed.

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Your Questions, Answered by Experts.

At Daze Puzzle, we understand that every clue is a puzzle within a larger puzzle. Our team of dedicated human experts and puzzle lovers solves these challenges daily to help you succeed. Below, we answer common questions about this specific clue.

A: The most common and recent 5-letter answer for "Significant blood line" is AORTA.

A: The clue uses the word 'significant' to indicate something important or crucial, and 'blood line' cleverly refers to a major blood vessel. The aorta is the main artery that carries blood away from the heart to the rest of the body, making it a 'significant blood line.'

A: This clue was last seen in the WSJ Crossword on May 08, 2026.

A: The aorta is the main artery in the human body, supplying oxygenated blood to the circulatory system.

A: major vessel, Artery from the heart, Conduit from a ventricle, Major artery, Iliac artery feeder

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Significant blood line WSJ Crossword Clue

Crossword Answer

Interactive Solver for Significant blood line Crossword Clue

Unlock the puzzle's secrets with Daze's progressive hints!

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Hint 2

Hint 3

Hint 4

Across

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Clue Analysis

Your Questions, Answered by Experts.

Q1: What is the most likely answer for the crossword clue "Significant blood line"?

Q2: Why is "AORTA" the answer to the clue "Significant blood line"?

Q3: In which puzzle was the clue "Significant blood line" last seen?

Q4: What does the word "AORTA" mean in this context?

Q5: What are some other crossword clues that share the same answer?

Today's Crossword Answers

Significant blood line WSJ Crossword Clue

Crossword Answer

Interactive Solver for Significant blood line Crossword Clue

Unlock the puzzle's secrets with Daze's progressive hints!

Hint 1

Hint 2

Hint 3

Hint 4

WSJ Crossword May 8 2026 Answers

Across

Down

Clue Analysis

Your Questions, Answered by Experts.

Q1: What is the most likely answer for the crossword clue "Significant blood line"?

Q2: Why is "AORTA" the answer to the clue "Significant blood line"?

Q3: In which puzzle was the clue "Significant blood line" last seen?

Q4: What does the word "AORTA" mean in this context?

Q5: What are some other crossword clues that share the same answer?

Today's Crossword Answers

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