Significant blood line WSJ Crossword Clue
Crossword Answer
Click ? to reveal letters one by one before showing the full answer.
Need a Hint? Try Solving It Yourself First
Use our Hints & Tips to uncover the answer.
Hint 1
hintHint 2
meaningHint 3
explanationWSJ Crossword May 8 2026 Answers
WSJ Crossword Archive
Need to check full list of WSJ Crossword Answers?
Play WSJ Crossword
Frequently Asked Questions About This Clue
The most common and recent 5-letter answer for "Significant blood line" is AORTA.
The clue uses the word 'significant' to indicate something important or crucial, and 'blood line' cleverly refers to a major blood vessel. The aorta is the main artery that carries blood away from the heart to the rest of the body, making it a 'significant blood line.'
This clue was last seen in the WSJ Crossword on May 08, 2026.
The aorta is the main artery in the human body, supplying oxygenated blood to the circulatory system.
Important blood line, major vessel, Artery from the heart, Conduit from a ventricle, Major artery
The clue “Significant blood line” is a classic crossword staple, frequently appearing in puzzles like the WSJ crossword. For the puzzle dated May 8 2026, the definitive 5-letter answer is: AORTA.
Expert Tip: When you’re stuck, try to analyze the structure of the clue itself. Is it a direct definition, a pun, a fill-in-the-blank, or a pop culture reference? Identifying the type of clue you’re dealing with is a key skill for improving your solving speed.
Finished the WSJ Puzzle? Check out this link for future puzzles:
Play the Official Game
Explore More Games
Discover more puzzle games, crossword answers and daily word-guessing games
